Manufacturer
GlaxoSmithKline Manufacturing S.p.A
Contents
Topotecan HCl
Indication
Ovarian carcinoma, Small cell lung cancer, Cervical cancer,
Instruction
Administer via IV Infusion by personnel healthcare.
Drug interaction
Increased clearance with phenytoin. G-CGF to be given 24 hr after completion of treatment with topotecan as concurrent admin may prolong duration of neutropenia. Increased bone marrow supression with other cytotoxic drugs (e.g. cisplatin) so dose reduction may be needed.
Malaysia
