Manufacturer
NOVARTIS PHARMA PRODUKTIONS GMBH
Contents
Vildagliptin 50mg + Metformin 500mg
Indication
Type 2 diabetes mellitus
Instruction
Should be taken with food. Take w/ or immediately after meals to reduce GI discomfort.
Drug interaction
Delayed elimination of metformin w/ cationic active substances eliminated by renal tubular secretion (e.g. cimetidine). Increased risk of lactic acidosis w/ ACE inhibitors, angiotension receptor antagonists, diuretics, NSAIDs. Increased risk of angioedema w/ ACE inhibitors. Thiazide diuretics, corticosteroids, phenothiazines, thyroid products, OC, sympathomimetics, phenytoin, niacin, Ca channel blockers and isoniazid may exacerbate loss of glycaemic control.Potentially Fatal: Intravascular admin of iodinated contrast agents may cause contrast-induced nephropathy, leading to increased risk of lactic acidosis.
Malaysia
