Indication
Hypertension
Instruction
May be taken with or without food.
Drug interaction
Increased exposure of simvastatin. May increased bioavailability w/ grapefruit juice. Increased systemic exposure w/ diltiazem. Increased plasma conc w/ strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir). Reduced plasma conc w/ CYP3A4 inducers (eg, rifampicin, St. John's wort).
Malaysia
