Manufacturer
ALLERGAN PHARMACEUTICALS IRELAND
Contents
Brimonidine Tartrate
Indication
Ocular hypertension, Open-angle glaucoma
Instruction
Instill 1 drop into affected eye(s) bid or tid (approx 8 or 12 hrly).
Drug interaction
TCAs (e.g. imipramine) and tetracyclic antidepressants (e.g. mianserin) that affect the metabolism and uptake of circulating amines may interfere w/ IOP-lowering effect brimonidine. Additive IOP-lowering and CV effects w/ β-blockers, antihypertensives, cardiac glycosides. Additive or potentiating effect w/ CNS depressants (e.g. barbiturates, opiates, sedatives or anaesthetics).
Potentially Fatal: Interfered metabolism and increased adverse effect when used w/ MAOIs (e.g. selegiline).
Malaysia
