Manufacturer
Takeda GmbH
Contents
Roflumilast
Indication
Maintenance treatment of severe COPD associated w/ chronic bronchitis in adult w/ history of frequent exacerbations as add-on to bronchodilator treatment.
Instruction
May be taken with or without food: Swallow w/ water. Take at the same time each day.
Drug interaction
Increased exposure & persistent intolerability w/ enoxacin, cimetidine, fluvoxamine. Reduced therapeutic efficacy w/ phenobarb, carbamazepine, phenytoin. Increased total PDE4 inhibitory activity w/ erythromycin, ketoconazole, theophylline, OCs.
Malaysia
