Manufacturer
FDC Ltd
Contents
Gentamicin 0.3%w/v (as gentamicin sulphate), Benzalkonium Chloride NF (as preservative)
Indication
Superficial ophthalmic infections
Instruction
Adult: As 0.3% eye drops: Instill 1-2 drops into affected eye up to 6 times daily. For severe infections, initially, 1-2 drops every 15 min, reducing the frequency gradually as the infection is controlled. As 0.3% eye oint: Place a small amount into the conjunctival sac 2-3 times daily.
Child: Same as adult dose.
Drug interaction
Additive effect w/ other neurotoxic and/or nephrotoxic drugs including cephalosporins, methicillin, amphotericin B, ciclosporin, cisplatin, potent diuretics (e.g. ethacrynic acid, furosemide) and neuromuscular blocking agents (e.g. succinylcholine, tubocurarine). May potentiate the effect of anticoagulants (e.g. warfarin, phenindione). May antagonise the effect of neostigmine and pyridostigmine. Increased risk of hypocalcaemia w/ bisphosphonates. Increased risk of neuromuscular blockade w/ botulinum toxin. Indometacin may increase the plasma concentration of gentamicin in neonates.
Malaysia
