Manufacturer
NOVARTIS SINGAPORE PHARMACEUTICAL MANUFACTURING PTD. LTD.
Contents
Per 100 mg FC tab Sacubitril 48.6 mg, valsartan 51.4 mg.
Indication
Symptomatic treatment of chronic heart failure w/ reduced ejection fraction in combination w/ other heart failure therapies in place of an ACE inhibitor or angiotensin II receptor blocker (ARB).
Instruction
May be taken with or without food.
Drug interaction
Contraindicated w/ ACE inhibitors. Not recommended w/ ARB-containing product. Combination w/ statins, sildenafil, K-sparing diuretics including mineral corticoid antagonists (eg, spironolactone, eplerenone), K supplements or K-containing salt substitutes, NSAIDs including selective COX-2 inhibitors, lithium, inhibitors of OATP1B1, OATP1B3, OAT3 (eg, rifampin, cyclosporine), OAT1 (eg, tenofovir, cidofovir) or MPR2 (eg, ritonavir).
Malaysia
