Manufacturer
GLAXOSMITHKLINE PHARMACEUTICALS SA
Contents
Lamotrigine
Indication
Adjunctive or monotherapy in treatment of epilepsy for partial & generalized seizures, including tonic-clonic seizures & seizures associated w/ Lennox-Gastaut syndrome. Bipolar disorder: Prevention of mood episodes predominantly by preventing depressive episode.
Instruction
May be taken with or without food: Tab: Swallow whole, do not chew/crush. Dispersible tab: May be chewed/dispersed in a small volume of water or swallowed whole w/ a little water.
Drug interaction
Inhibited glucuronidation by valproate. Induced glucuronidation by carbamazepine, phenytoin, primidone, phenobarb, rifampicin, lopinavir/ritonavir/atazanavir, ethinylestradiol/levonorgestrel combination. Increased topiramate conc. Reduced AUC & Cmax w/ OCs. False +ve reading for phencyclidine.
Malaysia
