Manufacturer
DUOPHARMA (M) SDN. BHD.
Contents
Dobutamine HCl
Indication
Acute heart failure, Cardiac stress test.
Instruction
Administer via IV infusion.
Drug interaction
Risk of hypotension and tachycardia w/ α-blockers (e.g. phenoxybenzamine). May produce ventricular arrhythmias w/ cyclopropane, halothane and other halogenated anaesth. Increased risk of arrhythmias w/ quinidine and cardiac glycosides. Risk of HTN and arrhythmias w/ TCAs. May increase BP w/ antihypertensives. Risk of severe HTN and bradycardia w/ β-blocker esp non-selective β-blockers. Reduced cardiotonic effects w/ CaCl infusion. Increased risk of HTN w/ doxapram. Enhanced effects w/ entacapone. Risk of ergotism w/ ergotamine or ergometrine (ergonovine) or methysergide. Oxytocin may possibly enhance the pressor effect of dobutamine w/ or w/o HTN.