Manufacturer
DUOPHARMA (M) SDN. BHD.
Contents
Timolol maleate
Indication
Open-angle glaucoma, Ocular hypertension
Instruction
Adult: Eye drop soln: Initially, instill 1 drop of 0.25% soln bid into the affected eye(s), may increase to 1 drop of 0.5% soln bid if there is inadequate response; decrease to 1 drop once daily if controlled. Do not exceed 1 drop bid of 0.5% soln. As 0.25% or 0.5% gel-forming eye drops: Instill 1 drop into the affected eye(s) once daily.
Drug interaction
Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive effects w/ other antihypertensives (e.g. hydralazine, methyldopa). Increased β-adrenergic blockade (e.g. decreased heart rate) w/ quinidine. Rebound HTN due to abrupt withdrawal of clonidine. Hypotensive effect may be antagonised by NSAIDs (e.g. indomethacin, ibuprofen).
Malaysia
