Manufacturer
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
Contents
Diphenoxylate HCl 2.5 mg, atropine sulfate 0.025 mg
Indication
Diarrhoea.
Instruction
Adult: Each tab or 5 mL soln contains diphenoxylate HCl 2.5 mg and atropine sulphate 0.025 mg: Initially, 5 mg 4 times daily, may reduce dose to 5 mg daily once satisfactory control is achieved. Max: 20 mg daily.
Drug interaction
Increased antimuscarinic side effects w/ amantadine, antihistamines, and TCAs. Antagonises the effect of domperidone, metoclopramide, bethanechol, carbachol, cisapride, galantamine, neostigomine, pyridostigmine, and pilocarpine. May potentiate CNS depressant effects of barbiturates and tranquilizers. May precipitate hypertensive crisis when concomitantly used w/ MAOIs. May reduce absorption of ketoconazole. May reduce plasma concentration of levodopa. Increased effect w/ memantine.
Malaysia
