Manufacturer
PHARMANIAGA LIFESCIENCE SDN. BHD.
Contents
Lignocaine HCl
Indication
Local anaesth, dental infiltration or nerve block, local infiltration, peripheral nerve block, sympathetic block & transtracheal anaesth.
Instruction
Infiltration anaesth 2% soln w/ adrenaline 1 in 100,000 to 1 in 500,000. Nerve block 1-2 mL of 2% soln. Dentistry 2% soln w/ adrenaline in 1 in 100,000 or noradrenaline 1 in 800,000.
Drug interaction
Antagonise effects of antimyasthenics on skeletal muscle. Additive depressant effect w/ CNS depressants. Release heavy metal ions from disinfectant soln which may cause severe local irritation, swelling & oedema. Excessive circulation restriction w/ methoxamine. Ischaemia leading to gangrene may result w/ other vasoconstrictors eg, adrenaline or phenylephrine. Increased risk of lignocaine toxicity (reduced metabolism) w/ β-adrenergic blocking agents. Inhibition of hepatic metabolism w/ cimetidine.
Malaysia
