Manufacturer
PHARMANIAGA MANUFACTURING BERHAD
Contents
Cefotaxime
Indication
Prophylaxis of surgical infections, Septicaemia, Bone and joint infections, Central nervous system infections, Genitourinary infections, Gynaecological infections, Intra-abdominal infections, Respiratory tract infections, Skin and skin structure infections and Gonorrhoea.
Instruction
Prophylaxis of surgical infections
Adult: 1 g 30-90 min before surgery by deep IM, slow IV inj over 3-5 min or IV infusion over 20-60 min. Caesarean section: 1 g IV as soon as the umbilical cord is clamped and 2 further IM or IV doses 6-12 hr later.
Septicaemia
Adult: Up to 6-8 g daily in 3-4 divided doses by deep IM, slow IV inj over 3-5 min or IV infusion over 20-60 min.
Bone and joint infections, Central nervous system infections, Genitourinary infections, Gynaecological infections, Intra-abdominal infections, Respiratory tract infections, Skin and skin structure infections
Adult: 1-2 g 8-12 hrly depending on the severity of the infection. May be given via deep IM inj, slow IV inj over 3-5 min or by IV infusion over 20-60 min. Max: 12 g daily.
Child: 0-1 wk 50 mg/kg/dose 12 hrly IV inj; >1-4 wk 50 mg/kg/dose 8 hrly IV inj; 1 mth to 12 yr <50 kg: 50-180 mg/kg IM or IV inj in 4-6 divided doses.
Gonorrhoea
Adult: 0.5 or 1 g as a single dose by deep IM, slow IV inj over 3-5 min or IV infusion over 20-60 min.
Drug interaction
Increased risk of nephrotoxicity w/ aminoglycosides. Increased serum concentration w/ probenecid
Malaysia
