Manufacturer
PHARMANIAGA MANUFACTURING BERHAD
Contents
Trihexyphenidyl Hydrochloride
Indication
Treatment of Parkinson's disease
Instruction
The starting dose is 1mg daily. This will be gradually increased until a maintenance dose of 515mg\ daily, in 3-4 divided doses is achieved. The maximum daily dose is 20mg. The dose will be determined for you by your doctor.
Elderly: Patients over 65 years may require a reduced adult dose.
Drug interaction
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. In particular: Other medicines that have an anti-muscarinic effect such as atropine, hyposcine, oxybutyninand tolterodine used to treat bowel or bladder problems. Monoamine oxidase inhibitors (MAOIs) used to treat depression e.g phenelzine, isocarboxzid. Antihistamines used to treat allergic reaction e.g diphenhydramine. Disopyramide used to treat an irregular heart beat. Phenothiazines used to treat mental disorders or nausea and vomiting e.g chlorpromazine, thioridazine and fluphenazine. Metoclopramide or domperidone used to treat the symptoms of nausea. Tricyclic antidepressants e.g. amitriptyline. Nefopam used to treat pain. Ketoconazole used to treat fungal infections. Other medicines used in the treatment of Parkinson's disease e.g amantidine and levodopa. Medicines used to stimulate the nervous system. If you use nitrate tablets under your tongue to treat angina attacks, you may find that trihexyphenidyl makes your mouth too dry to dissolve them.
Malaysia
