Diovan 40mg Film-Coated Tablet

Manufacturer

NOVARTIS FARMACEUTICA S.A.

 

Contents

Valsartan

 

Indication

HTN, heart failure, post MI.

 

Instruction

May be taken with or without food.

 

Drug interaction

Increased incidence of hypotension, hyperkalemia & changes in renal function w/ other drugs blocking RAS eg, ACE inhibitors or aliskiren. Increased serum K levels w/ K-sparing diuretics or K supplements. Decreased antihypertensive effects w/ NSAIDs including COX-2 inhibitors. Increased systemic exposure to valsartan w/ inhibitor of the uptake transporter (rifampin, ciclosporin) or efflux transporter (ritonavir). Increased lithium conc & toxicity.