Manufacturer
NOVARTIS PHARMA STEIN AG
Contents
Basiliximab
Indication
Prophylaxis of acute organ rejection in de novo renal transplantation in adult & childn, to be used concomitantly w/ ciclosporin for microemulsion & corticosteroid-based immunosuppression; or in a triple therapy regimen w/ ciclosporin, corticosteroids & either azathioprine or mycophenolate mofetil.
Instruction
2 doses, the 1st dose w/in 2 hr before transplantation surgery, & the 2nd 4 days after transplantation. Adult & childn ≥35 kg 20 mg/dose; <35 kg 10 mg/dose.
Drug interaction
Because Simulect is an immunoglobulin, no metabolic drug-drug interactions are to be expected.
Concomitant Medications Routinely Administered in Organ Transplantation: In addition to ciclosporin for microemulsion, steroids, azathioprine and mycophenolate mofetil, other concomitant medications