Mô tả
Manufacturer
Pfizer
Contents
Natural conjugated estrogens
Indication
Premarin is a mixture of estrogen hormones used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Other uses include prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. Premarin is sometimes used as part of cancer treatment in women and men. Premarin should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.
Instruction
Use Premarin as directed by your doctor.
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Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.
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Premarin is taken on a daily basis. For certain conditions, Premarin is given in a cycle, such as 25 days on followed by 5 days. Follow the directions on your prescription label.
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Premarin may be taken by mouth with or without food.
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Take Premarin with a full glass of water.
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Try to take the medicine at the same time each day.
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Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Premarin.
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It is important to take Premarin regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
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To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your thyroid function may also need to be tested. Do not miss any scheduled appointments.
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If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Premarin. You may need to stop using the medicine for a short time.
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This medication can affect the results of certain medical tests. Tell any doctor who treats you that you are using Premarin.
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If you miss a dose of Premarin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Premarin.
Drug interaction
Estrogens stimulate the liver's ability to produce factors that promote the clotting of blood. Thus, concomitant administration of Premarin and warfarin (blood thinner) may cause decrease their effects. Barbiturates, Rifampin (Rifadin), phenytoin (Dilantin), carbamazepine (Tegretol), griseofulvin (Grifulvin), St. John's wort and primidone increase metabolism of estrogens. Erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and ritonavir (Norvir) act oppositely.
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