Vytorin 10/10mg

Vytorin 10/10mg

Danh mục: Drug Info Có sẵn
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Mô tả

Manufacturer
Merck Sharp & Dohme
 
Contents
Ezetimibe 10 mg, simvastatin 10 mg
 
Indication
Vytorin is used for treating high cholesterol along with a cholesterol-lowering diet. Vytorin is a combination of 2 medicines. Ezetimibe works by reducing the amount of cholesterol that your body absorbs from your diet. Simvastatin is an HMG-CoA reductase inhibitor or 'statin.' It works by blocking an enzyme that is necessary for your body to make cholesterol. Lowering cholesterol levels in the blood reduces the chance of heart disease, heart attacks, and strokes. Vytorin has not been shown to reduce heart attacks or strokes more than simvastatin alone.
 
Instruction
Use Vytorin as directed by your doctor.

Ask your health care provider any questions you may have about how to use Vytorin.
 
 
Drug interaction
Increased risk of myopathy/rhabdomyolysis w/ potent CYP3A4 inhibitors (eg, itraconazole, ketoconazole, posaconazole, voriconazole, erythromycin, clarithromycin, telithromycin, HIV-PIs, boceprevir, telaprevir or nefazodone & drugs containing cobicistat); gemfibrozil, cyclosporine, danazol; fusidic acid; amiodarone, Ca channel blockers (verapamil, diltiazem, amlodipine); lomitapide, moderate inhibitors of CYP3A4; niacin; colchicine; grapefruit juice. Fibrates (except fenofibrate). Decreased mean AUC w/ cholestyramine. Increased INR w/ coumarin anticoagulants (eg, warfarin). Decreased absorption w/ antacids.

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