Manufacturer
Apex
Contents
Atorvastatin Calcium
Indication
Heterozygous familial hypercholesterolaemia; Nonfamilial hypercholesterolaemia; Mixed dyslipidaemia Familial homozygous hypercholesterolaemia and Prophylaxis of cardiovascular events in high-risk patient.
Instruction
May be taken with or without food. Avoid excessive consumption (>1 L/day) of grapefruit juice. Adult: PO Heterozygous familial hypercholesterolaemia; Nonfamilial hypercholesterolaemia; Mixed dyslipidaemia Dose is individualised according to baseline LDL-C levels, the goal of therapy, and patient response. Usual initial dose: 10 or 20 mg once daily, may be adjusted according to response at 2-4 weeks interval. Usual range: 10-80 mg once daily. Max: 80 mg/day. Familial homozygous hypercholesterolaemia as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis): 10-80 mg daily. Prophylaxis of cardiovascular events in high-risk patient Primary prevention: Initial: 10 mg daily, may be given at higher doses as necessary to attain LDL-cholesterol levels according to current guidelines.