Manufacturer
APOTEX INC
Contents
Propranolol HCl
Indication
Treat patient with Hypertension, Portal hypertension, Angina pectoris, Prophylaxis of migraine, Myocardial infarction, Phaeochromocytoma, Cardiac arrhythmias, Essential tremor, Anxiety, Hypertrophic cardiomyopathy and Hyperthyroidism.
Instruction
Tab: Should be taken on an empty stomach.
Cap: May be taken with or without food. Take consistently either always w/ or always w/o meals.
Drug interaction
May have potentiating effects on arterial conduction time and induce additive negative or inotropic effect with propafenone, amiodarone, quinidine, flecainide and Ca channel blockers. Concomitant administration with catecholamine-depleting drugs (e.g. reserpine), MAOIs or TCAs may cause additive effects and potentiate hypotension. Reduced antihypertensive effect with NSAIDs (e.g. ibuprofen, indometacin). May enhance vasoconstrictive action of ergot alkaloids. Coadministration with warfarin increases its bioavailability and prothrombin time. May enhance hypoglycaemic effects of insulin. Increased risk of hypotension and attenuation of the reflex tachycardia with anaesthetic drugs. Increased plasma concentration with lidocaine.
Malaysia
