Manufacturer
APOTEX INC
Contents
Acetazolamide
Indication
Epilepsy, Diuresis, Oedema, Adjunct in open-angle glaucoma, Preoperative management of angle-closure glaucoma and Prophylaxis of high-altitude disorders.
Instruction
Should be taken with food.
Drug interaction
May increase serum levels of anticonvulsants (e.g. phenytoin, carbamazepine). May potentiate the effects of folic acid antagonists, hypoglycaemics, and oral anticoagulants. May require dose adjustments when co-administered with cardiac glycosides or hypertensive agents. May increase excretion of lithium. May reduce serum level of primidone. May enhance effects of amphetamines and quinidine. May prevent the urinary antiseptic effect of methenamine. May elevate serum ciclosporin levels. Increased risk of renal calculus formation with Na bicarbonate.Potentially Fatal: Increased risk of severe acidosis and CNS toxicity with high-dose aspirin.