Manufacturer
Aurobindo Pharma Limited (Unit XII)
Contents
Per 1.5 g powd for inj Ampicillin Na 1,000 mg, sulbactam Na 500 mg. Per 3 g powd for inj Ampicillin Na 2,000 mg, sulbactam Na 1,000 mg
Indication
Upper & lower resp tract infections eg, sinusitis, otitis media & epiglottitis; bacterial pneumonia; UTI & pyelonephritis; intra-abdominal infections eg, peritonitis, cholecystitis, endometritis & pelvic cellulitis; bacterial septicemia; skin, soft tissue, bone, joint & gonococcal infections. Peri-op prophylaxis for post-op sepsis reduction in abdominal or pelvic surgery & in termination of pregnancy or cesarean section.
Instruction
Sulbactam sodium/ampicillin sodium IM/IV can be administered by either intravenous or intramuscular routes.
Drug interaction
Increased incidence of rashes w/ allopurinol. Substantial mutual inactivation w/ aminoglycosides. Additive effects w/ anticoagulants. Interfered bactericidal effects by bacteriostatic drugs eg, chloramphenicol, erythromycin, sulfonamides & tetracyclines. Reduced effectiveness of estrogen-containing OCs. Decreased clearance & toxicity of methotrexate. Decreased renal tubular secretion by probenecid. False +ve glycosuria test.
Malaysia
