Olimel N9E, Emulsion for Infusion

Manufacturer
BAXTER S.A,
 
Contents
Olimel N9E Per 1,000 mL Refined olive oil + refined soy bean oil 40 g, alanine 8.24 g, arginine 5.58 g, aspartic acid 1.65 g, glutamic acid 2.84 g, glycine 3.95 g, histidine 3.4 g, isoleucine 2.84 g, leucine 3.95 g, lysine 4.48 g (lysine acetate 6.32 g), methionine 2.84 g, phenylalanine 3.95 g, proline 3.4 g, serine 2.25 g, threonine 2.84 g, tryptophan 0.95 g, tyrosine 0.15 g, valine 3.64 g, Na acetate trihydrate 1.5 g, hydrated Na glycerophosphate 3.67 g, KCl 2.24 g, Mg chloride hexahydrate 0.81 g, Ca chloride dihydrate 0.52 g, glucose anhydrous 110 g (glucose monohydrate 121 g). Per 1,500 mL Refined olive oil + refined soy bean oil 60 g, alanine 12.36 g, arginine 8.37 g, aspartic acid 2.47 g, glutamic acid 4.27 g, glycine 5.92 g, histidine 5.09 g, isoleucine 4.27 g, leucine 5.92 g, lysine 6.72 g (lysine acetate 9.48 g), methionine 4.27 g, phenylalanine 5.92 g, proline 5.09 g, serine 3.37 g, threonine 4.27 g, tryptophan 1.42 g, tyrosine 0.22 g, valine 5.47 g, Na acetate trihydrate 2.24 g, hydrated Na glycerophosphate 5.51 g, KCl 3.35 g, Mg chloride hexahydrate 1.22 g, Ca chloride dihydrate 0.77 g, glucose anhydrous 165 g (glucose monohydrate 181.5 g). Per 2,000 mL Refined olive oil + refined soy bean oil 80 g, alanine 16.48 g, arginine 11.16 g, aspartic acid 3.3 g, glutamic acid 5.69 g, glycine 7.9 g, histidine 6.79 g, isoleucine 5.69 g, leucine 7.9 g, lysine 8.96 g (lysine acetate 12.64 g), methionine 5.69 g, phenylalanine 7.9 g, proline 6.79 g, serine 4.5 g, threonine 5.69 g, tryptophan 1.9 g, tyrosine 0.3 g, valine 7.29 g, Na acetate trihydrate 2.99 g, hydrated Na glycerophosphate 7.34 g, KCl 4.47 g, Mg chloride hexahydrate 1.62 g, Ca chloride dihydrate 1.03 g, glucose anhydrous 220 g (glucose monohydrate 242 g).
 
Indication
Central parenteral nutrition for critically ill adult patients when oral or enteral nutrition is impossible, insufficient or contraindicated
 
Instruction
For single use only.
It is recommended that, after opening the bag, the contents are used immediately and not stored for subsequent infusion.
For instructions for preparation and handling of the emulsion for infusion see Special precautions for disposal and other handling under Cautions for Usage.
Due to its high osmolarity, OLIMEL can only be administered through a central vein.
The recommended duration of infusion for a parenteral nutrition bag is between 12 and 24 hours.
Only administer the product after the non-permanent seals between the three compartments have been broken and the contents of the three compartments have been mixed.
Ensure that the final emulsion for infusion does not show any evidence of phase separation.
After opening the bag the content must be used immediately. It must never be stored for a subsequent infusion. Do not reconnect any partially used bag.
Do not connect in series in order to avoid the possibility of gas embolism due to air contained in the first bag.
Any unused product or waste material and all necessary devices must be discarded.
 
Drug interaction
Possibility of pseudoagglutination when administered simultaneously w/ blood through the same infusion tubing. Precipitation of ceftriaxone-Ca can occur when ceftriaxone is mixed w/ Ca-containing soln in the same IV administration line. Risk of hyperkalaemia w/ K-sparing diuretics (eg, amiloride, spironolactone, triamterene), ACE inhibitors, AIIA, tacrolimus or cyclosporine.