Manufacturer
BAYER AG
Contents
Ciprofloxacin
Indication
Infections of the resp tract, middle ear, paranasal sinuses, eyes, kidneys &/or efferent urinary tract, genital organs, abdominal cavity, skin & soft tissues, bones & joints; sepsis, prophylaxis of infections & for selective intestinal decontamination in immunosuppressed patients. Oral: Prophylaxis of invasive infections due to N meningitidis. Inhalational anthrax in adults & childn.
Instruction
May be taken with or without food: May be taken on an empty stomach for better absorption. Do not take w/ dairy products (eg, milk, yoghurt) or mineral-fortified fruit juice (eg, Ca-fortified orange juice).
Drug interaction
Class IA or III antiarrhythmics, multivalent cation-containing prep & mineral supplements, polymeric phosphate binders, sucralfate or antacids, highly buffered drugs containing Mg, Al, Ca, dairy products or mineral fortified drinks. Increased serum conc w/ probenecid. Increased serum conc of tizanidine, theophylline, caffeine, pentoxifylline. Increased absorption w/ metoclopramide. Slight reduction of Cmax & AUC w/ omeprazole. Inhibit renal tubular transport of methotrexate. Induced convulsions w/ NSAIDs. Increased serum creatinine conc w/ cyclosporin. Augmented anticoagulant effects of vit K antagonist. Intensified action of glibenclamide. Increased AUC & Cmax of duloxetine, ropinirole & sildenafil. Reduced clearance of lidocaine IV.
Malaysia
