Manufacturer
JANSSEN PHARMACEUTICA N.V.
Contents
Itraconazole
Indication
Cap: Vulvovag & oral candidosis; dermatomycosis, plantar tinea pedis & palmar tinea manus, pityriasis versicolor; onychomycosis; systemic aspergillosis & candidosis; cryptococcosis eg, cryptococcal meningitis; histoplasmosis; blastomycosis; lymphocutaneous/cutaneous & extracutaneous sporotrichosis; paracoccidioidomycosis; chromomycosis. Oral soln: Oral &/or esophageal candidosis in HIV-positive or other immunocompromised patients. Prophylaxis of deep fungal infections.
Instruction
Oral soln: Should be taken on an empty stomach: Refrain from eating for at least 1 hr after intake.
Drug interaction
Decreased bioavailability w/ moderate or potent CYP3A4 inducers. Increased bioavailability w/ moderate or potent CYP3A4 inhibitors. Impaired absorption w/ drugs reducing gastric acidity. Inhibited metabolism of CYP3A4 metabolized drugs. Increased plasma conc of P-glycoprotein &/or breast cancer resistance protein drugs.
Malaysia
