Manufacturer
Pfizer Manufacturing Deutschland GmbH.
Contents
Tofacitinib
Indication
Adult patients w/ moderately to severely active RA who had an inadequate response or intolerance to methotrexate (MTX), as monotherapy or in combination w/ MTX or other nonbiologic disease-modifying anti-rheumatic drugs. Not recommended to use in combination w/ biologic DMARDs or potent immunosuppressants eg, azathioprine & cyclosporine.
Instruction
May be taken with or without food.
Drug interaction
Potent CYP3A4 inhibitors (eg, ketoconazole) & inducers (eg, rifampin), moderate CYP3A4 & potent CYP2C19 inhibitors (eg, fluconazole) & immunosuppressive drugs (eg, azathioprine, tacrolimus, cyclosporine).
Malaysia
