Eliquis 5mg

Eliquis 5mg

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详情

Manufacturer
Pfizer
 
Contents
Apixaban
 
Indication
Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.
 
Instruction

 
Drug interaction
CYP3A4 & P-gp inhibitors: Increased plasma conc w/ azole antimycotics (eg, ketoconazole, itraconazole, voriconazole & posaconazole) & HIV-PIs (eg, ritonavir); diltiazem, naproxen, amiodarone, verapamil, quinidine. CYP3A4 & P-gp inducers: Decreased plasma conc w/ rifampicin; phenytoin, carbamazepine, phenobarb or St. John's wort. Increased bleeding risk w/ other anticoagulants, platelet aggregation inhibitors & NSAIDs including ASA. Serious bleeding risk w/ thrombolytic agents, GPIIb/IIIa receptor antagonists, thienopyridines (eg, clopidogrel), dipyridamole, dextran & sulfinpyrazone. Reduced exposure w/ activated charcoal.

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