U-Closone Ointment

U-Closone Ointment

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Manufacturer
HOE PHARMACEUTICALS SDN. BHD.
 
Contents
Clobetasone butyrate
 
Indication
All types of eczema & dermatitis including atopic eczema, photodermatitis, otitis externa, primary irritant & allergic dermatitis prurigo nodularis, seborrhoeic dermatitis & insect bite reactions. Maintenance between courses of more potent topical steroids in more resistant dermatoses.
 
Instruction
Apply up to 4 times a day until condition improves, then reduce frequency.
 
Drug interaction
Increased systemic exposure w/ CYP3A4 enzyme inhibitors (e.g. itraconazole, ritonavir). May diminish the antineoplastic effect of aldesleukin. May potentiate the hyperglycaemic effect of ceritinib. May diminish the therapeutic effect of corticorelin and hyaluronidase. May enhance the adverse/toxic effects of deferasirox.
 

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