Manufacturer
FRESENIUS KABI AUSTRIA GMBH
Contents
Rocuronium bromide
Indication
Facilitate endotracheal intubation, Facilitate mechanical ventilation in intensive care, Muscle relaxant in general anaesthesia
Instruction
Adult: Initially, 0.6 mg/kg by inj. Higher doses of 1 mg/kg may be used for intubation during rapid sequence induction of anaesthesia. Maintenance: 0.15 mg/kg by inj (may reduce to 0.075-1 mg/kg for prolonged inhalational anaesthesia) or by infusion at 0.3-0.6 mg/kg/hr.
Child: Same as adult dose.
Elderly: Maintenance: 0.075-1 mg/kg.
Drug interaction
Increased effect w/ halogenated volatile anaesth (e.g. enflurane, isoflurane), antibiotics (e.g. aminoglycoside, lincosamide and polypeptide antibiotics, acylamino-penicillin antibiotics), diuretics, quinidine, quinine, Mg and lithium salts, Ca channel blockers, local anaesth, acute admin of phenytoin or β-blocking agents, corticosteroid (long-term use) and after intubation w/ suxamethonium. Decreased effect w/ Ca chloride and KCl, protease inhibitors (e.g. gabexate, ulinastatin), chronic admin of phenytoin or carbamazepine.
Malaysia
