Manufacturer
DUOPHARMA (M) SDN. BHD.
Contents
Gentamicin sulphate
Indication
Superficial ophthalmic infections and Otitis externa.
Instruction
Otitis externa As 0.3% ear drops: Instill 2-3 drops in the affected ear 3-4 times a day and at night. Ophth Superficial opth infections As 0.3% eye drops: Instill 1-2 drops into affected eye up to 6 times/day, or more frequently if required
Drug interaction
Additive effect w/ other neurotoxic and/or nephrotoxic drugs including cephalosporins, methicillin, amphotericin B, ciclosporin, cisplatin, potent diuretics (e.g. ethacrynic acid, furosemide) and neuromuscular blocking agents (e.g. succinylcholine, tubocurarine). May potentiate the effect of anticoagulants (e.g. warfarin, phenindione). May antagonise the effect of neostigmine and pyridostigmine. Increased risk of hypocalcaemia w/ bisphosphonates. Increased risk of neuromuscular blockade w/ botulinum toxin. Indometacin may increase the plasma concentration of gentamicin in neonates.
Malaysia
